Twenty teams in Fort Frances will walk the track at Fort Frances High School for 12 hours in support of the Canadian Cancer Society.
Chair Jennifer Anderson says the public is invited to participate.
This year's theme is around the game Monopoly.
The event begins with cancer survivors gathering for a dinner at 4:30 p.m.
Opening ceremonies will take place at 6:30 p.m. before the open lap at 7 p.m.
Rainy River's Relay For Life is at Riverview School.
It begins with a survivors' dinner at 5 p.m. before the ten teams involved take to the track at 7 p.m..
Committee member Georgia Kreger says this theme is "Decades of Hope" with team dressing up to celebrate their favourite decade of time.
The fundraising goal has been set at $55-thousand.
Luminary ceremonies are planned at both events at around 10 p.m.
